by Sharon Kuttner | Jul 29, 2020 | Stroke Research
Abstract Ischaemia-induced tissue injury has wide-ranging clinical implications including myocardial infarction, stroke, compartment syndrome, ischaemic renal failure and replantation and revascularization. However, the restoration of blood flow produces a...
by Sharon Kuttner | Jul 29, 2020 | Stroke Research
Abstract Background/Purpose Repetitive hyperbaric oxygen (HBO2) therapy may cause excessive generation of reactive oxygen species. This study assessed whether repetitive or 2–4-day trials of HBO2 therapy (2 treatments daily for 2–4 consecutive days) provides better...
by Sharon Kuttner | Jul 29, 2020 | Stroke Research
Abstract Intravenous recombinant tissue-type plasminogen activator (r-tPA, alteplase) remains the recommended therapy for acute ischemic stroke. However, several factors are limiting its practical use. It makes it urgent for us to search more efficient strategies that...
by Sharon Kuttner | Jul 29, 2020 | Stroke Research
Abstract Background. While research suggests a benefit of hyperbaric oxygen therapy (HBOT) for neurologic injury, controlled clinical trials have not been able to clearly define the benefits. Objective. To investigate the effects of HBOT on physical and cognitive...
by Sharon Kuttner | Jul 29, 2020 | Stroke Research
Abstract Brain injury is the leading cause of death and disability worldwide and clinically there is no effective therapy for neuroprotection. Hyperbaric oxygen preconditioning (HBO-PC) has been experimentally demonstrated to be neuroprotective in several models and...
by Sharon Kuttner | Jul 29, 2020 | Stroke Research
Abstract Stroke continues to be an extremely prevalent disease and poses a great challenge in developing safe and effective therapeutic options. Hyperbaric oxygen therapy (HBOT) has demonstrated significant pre-clinical effectiveness for the treatment of acute...
