Hyperbaric Oxygen Therapy Research
A new combination therapy in severe acute pancreatitis–hyperbaric oxygen plus 3-aminobenzamide: an experimental study
Abstract Objectives This study was designed to evaluate effects of hyperbaric oxygen (HBO) plus 3-aminobenzamide (3-AB) cotreatment on tissue oxidative stress parameters (TOSp), tissue histopathology scores (THSc), and bacterial translocations (Bact-Trans) in an...
Combined application of dexamethasone and hyperbaric oxygen therapy yields better efficacy for patients with delayed encephalopathy after acute carbon monoxide poisoning
Abstract Background: Delayed encephalopathy after acute carbon monoxide (CO) poisoning (DEACMP) commonly occurs after recovering from acute CO poisoning. This study was performed to assess the efficacy of the combined application of dexamethasone and hyperbaric oxygen...
Hyperbaric oxygen therapy in patients with hypoxic ischemic encephalopathy
Abstract Background and Aim: To assess the efficacy of hyperbaric oxygen therapy (HBOT) in patients with hypoxic ischemic encephalopathy (HIE). Design: Non-randomized case-control observational study. Setting: Tertiary level neurorehabilitation unit....
Hyperbaric oxygen therapy can diminish fibromyalgia syndrome–prospective clinical trial
Abstract Background Fibromyalgia Syndrome (FMS) is a persistent and debilitating disorder estimated to impair the quality of life of 2–4% of the population, with 9:1 female-to-male incidence ratio. FMS is an important representative example of central nervous system...
Hyperbaric Oxygen Therapy for Second-Degree Burn Healing: An Experimental Study in Rabbits
Abstract BACKGROUND: The wound healing process includes inflammation, proliferation, and remodelling phases, the main features of which are inflammation, neoangiogenesis, and epithelialization. Hyperbaric oxygen therapy (HBOT) is one modality postulated to...
Systematic review: The safety and efficacy of hyperbaric oxygen therapy for inflammatory bowel disease
Summary Background Hyperbaric oxygen therapy (HBOT ) provides 100% oxygen under pressure, which increases tissue oxygen levels, relieves hypoxia and alters inflammatory pathways. Although there is experience using HBOT in Crohn's disease and ulcerative colitis, the...
Clinical Outcomes and Mortality Impact of Hyperbaric Oxygen Therapy in Patients With Carbon Monoxide Poisoning
Abstract Objective Carbon Monoxide (CO) poisoning affects 50,000 per year in the United States alone. Mortality is approximately 3% and up to 40% of survivors suffer from permanent neurocognitive and affective deficits. Hyperbaric oxygen therapy (HBO2) has shown...
Hyperbaric oxygen therapy facilitates healing of chronic foot ulcers in patients with diabetes
Abstract OBJECTIVE Chronic diabetic foot ulcers are a source of major concern for both patients and health care systems. The aim of this study was to evaluate the effect of hyperbaric oxygen therapy (HBOT) in the management of chronic diabetic foot ulcers. RESEARCH...
Hyperbaric oxygen protects against myocardial reperfusion injury via the inhibition of inflammation and the modulation of autophagy
Abstract Our previous study demonstrated that hyperbaric oxygen (HBO) preconditioning protected against myocardial ischemia reperfusion injury (MIRI) and improved myocardial infarction. However, HBO’s effect on MIRI-induced inflammation and autophagy remains unclear....
Effects of hyperbaric oxygen therapy on neuropathic pain via mitophagy in microglia
Abstract Purpose Hyperbaric oxygen (HBO) therapy has been suggested to palliate neuropathic pain, but the mechanisms involved are not well understood. This study explored the involvement of microglial mitophagy via HBO relative to neuropathic pain therapy. Materials...